A single vaccine would be enough against all Sars-CoV-2 variants

Hyperaxion Sep 3, 2020

According to scientists, the new coronavirus has undergone little change since it spread around the world, which facilitates the development of a vaccine.

After analyzing the Sars-CoV-2 genome in more than 27,000 people with Covid-19, scientists at the Walter Reed Army Institute of Research in the United States concluded that the new coronavirus has undergone few mutations since December 2019.

A single vaccine would be enough against all Sars-CoV-2 variants
(Credit: NIAID-RML).

According to an article published by the team in the Proceedings of the National Academy of Sciences earlier this week, this suggests that just one vaccine would be enough to stop the pandemic.

To classify variations of the microorganism, scientists analyzed 18,514 genomes of the virus that affected patients in 84 countries. According to them, the analyzes reveal few genetic variations of Sars-CoV-2, and these mutations occurred at random.

One of the mutations, D614G, which occurred in the spike protein of the new coronavirus, cannot be linked to specific adaptive forces.

According to the scientists, further studies on this variant are needed to understand the consequences of this mutation.

“Viral diversity has challenged vaccine development efforts for other viruses such as HIV, influenza and dengue, but global samples show SARS-CoV-2 to be less diverse than these viruses,” said Morgane Rolland, study leader and chief of viral genetics and systems serology for the WRAIR Military HIV Research Program.

“We can therefore be cautiously optimistic that viral diversity should not be an obstacle for the development of a broadly protective vaccine against COVID-19 infection.”

Related topics:

Coronavirus Covid-19

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